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Partnership includes recovery and downstream process optimization, and cGMP bulk drug substance manufacturing of CRM197.
July 27, 2023
By: Anthony Vecchione
Fina Biosolutions has selected Scorpius BioManufacturing, a biologics CDMO, for the production of an E.coli-expressed CRM197 conjugate vaccine carrier protein. The partnership includes recovery and downstream process optimization, analytical method implementation and phase-appropriate validation, scale-up, and cGMP bulk drug substance manufacturing of CRM197, a genetically detoxified diphtheria toxin widely used in conjugate vaccines. FinaBio markets their CRM197 under the tradename EcoCRM. ...
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